ONGOING & DEVELOPING RESEARCH PROJECTS

   Serum Glycoprotein Markers of Pancreatic Cancer.

INVESTIGATORS:      Marie H. Hanigan, PhD, Richard D. Cummings, Ph.D.

   Development of a Blood Test for Pancreatic Cancer using Proteomic Profiling.

INVESTIGATORS:      Jay Hanas, PhD, Russell Postier, MD, Daniel Brackett.

   Identification of Molecular Therapeutic Targets in Pancreatic Cancer

            INVESTIGATORS:     Russell Postier, MD, Megan Lerner, HT (ASCP), Jay Hanas, PhD;

            Eldon Jupe, PhD; Zoltan Laszik, MD, PhD; Daniel Brackett.

   Multigenic Assessment of Pancreatic Cancer Risk.

INVESTIGATORS:      Eldon Jupe, PhD,  John Mulvihill, MD, Chris Aston, PhD.

   Targeted Therapy of Pancreatic Cancer Using an Anti-Mesothelin Immunotoxin.

INVESTIGATORS:      Raffit Hassan, MD, Howard Ozer, MD, PhD.

   Genetic Epidemiology of Pancreatic Cancer.

INVESTIGATORS:      Chris Aston, PhD, Morris Foster, PhD, John Mulvihill, MD.

   Communication and Decision Making Strategies for Treatment and Control of Pancreatic Cancer.

INVESTIGATORS:      Dan O’Hair, PhD,  Paula Kim

   Endoscopic Ultrasound Screening for Pancreatic Cancer in a High Risk Cohort

INVESTIGATORS:      William Tierney, MD

   Chromosomal Instability as a Target for Therapy in Pancreatic Cancer.

INVESTIGATORS:      Gary Gorbsky, PhD.

   Identification of Therapeutic Targets to Prevent Pancreatic Cancer Metastasis.

INVESTIGATORS:      Thomas Pento, PhD, Xiaoping Zang, MD, PhD.

   Pancreatic Intraepithelial Neoplasia (PanIN): Morphologic and Proteomic Evaluation.

INVESTIGATORS:      Zoltan Laszik, MD, PhD,  Jay Hanas, PhD.

   Polyphenolic Compounds Reduce or Prevent Metastatic Bone Disease in a Orthotopic-Induced Pancreatic Cancer Rat Model.

INVESTIGATORS:      Brenda Smith, PhD, Megan Lerner, HCT (ASCP), Bahram Arjmandi, PhD, Michael Bronze, MD.

   Overexpression of erbB-2 and EGFR in Pancreatic Cancers and the Significance in Targeted Therapy.

INVESTIGATORS:      XiaoHe Yang, PhD.

   Mechanisms of Tumor-Mediated Angiogenesis in Pancreatic Cancer: The Role of Hypoxia.

INVESTIGATORS:      Eric Howard, PhD.

   Career Development of Surgery Residents with an Emphasis on Pancreatic Cancer Translational Research.

            INVESTIGATORS:      Larry Pennington, MD;  Russell Postier, MD;  Daniel Brackett.

RESOURCES & SUPPORT

   Human Tissue Core Laboratory

Co-Directors:  Zoltan Laszik, MD, PhD; Andre Kajdacsy, MD, PhD, Megan Lerner, HT(ASCP)

Contributing Faculty: Roxie Albrecht, MD; Larry Pennington, MD; Ronald Squires, MD;

   Animal Model / Cell Line Core Laboratory

Co-Directors:  Megan Lerner HT(ASCP); Yuriy Gusev, PhD.

   Population and Familial Ascertainment Core Laboratory                  

            Co-Directors: Chris Aston, PhD; Morris Foster, PhD,  John Mulvihill, MD.

   Molecular Oncology Core Laboratory

            Co-Director: Daniel Brackett, Megan Lerner, HT(ASCP),  Zoltan Laszik, MD, PhD,  Jay   

            Hanas, PhD. 

   Biostatistics Core Laboratory

            Co-Directors:  Yuriy Gusev, PhD, Mary Lane, PhD.

Copyright © 2002 Department of Surgery, OUHSC.  All rights reserved.