|
|
»
Faculty Researchers
|
Alphabetical by Researcher's Last Name (includes primary appointment and adjunct appointments)
A, B, C, D,
E, F, G, H,
I, J, K, L,
M, N, O, P,
Q, R, S, T,
U, V, W, X,
Y, Z
Health Sciences Center - Oklahoma City Campus
Oklahoma Medical Research Foundation (OMRF)
OU Health Sciences Center - Tulsa
OU - Norman
Veterans Administration (VA)
Top of the Page
|
A (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Gillian Air, Ph.D.
E-Mail Dr. Air
|
OUHSC: Biochemistry & Molecular Biology
|
Molecular approaches to control of influenza.
|
Darrin R. Akins, Ph.D.
E-Mail Dr. Akins
|
OUHSC: Microbiology & Immunology
|
Molecular biology and host-pathogen interactions of Borrelia burgdorferi, the causative agent of Lyme disease; functional genomics and proteomics of Borrelia burgdorferi; discovery and generation of novel vaccines and serodiagnostic tools for Lyme disease.
|
Petar Alaupovic, Ph.D.
E-Mail Dr. Alaupovic
|
OMRF: Lipid Studies
|
Research activities are centered around the chemistry, metabolism and pathophysiology of human plasma lipoproteins. One of the main aims of this Laboratory is to characterize chemically and metabolically major plasma lipoproteins defined by their apolipoprotein composition rather than the traditional density characteristics.
|
Anita C. All, RN, Ph.D.
E-Mail Dr. All
|
OUHSC: Nursing
|
Chronic illness, chronic pain and quality of life and education to reduce anxiety.
|
Muayyad R. Al-Ubaidi, Ph.D.
E-Mail Dr. Al-Ubaidi
|
OUHSC: Cell Biology (Vice Chair),
Neuroscience
|
Understanding the molecular events leading to cell death in retinal diseases.
|
Mark A. Anderson, Ph.D., P.T., A.T.C.
E-Mail Dr. Anderson
|
OUHSC: Rehabilitation Science
|
Sports medicine, rehabilitation of sports-related injuries, physiological factors related to sports performance, physical fitness.
|
Robert E. Anderson, M.D., Ph.D.
E-Mail Dr. Anderson
|
OUHSC: Cell Biology (Chair),
Neuroscience,
Ophthalmology
|
Phosphoinositide signaling pathways, polyunsaturated fatty acid (PUFA) metabolism, N-myristoyl transferases, neuroprotective agents, biochemical mechanisms of retinal degeneration, and control of phosphoinositide synthesis.
|
Cheryl B. Aspy, Ph.D.
E-Mail Dr. Aspy
|
OUHSC: Family & Preventive Medicine
|
(1) The impact of youth assets on youth risk behaviors such as sexual activity; alcohol, tobacco, and drug use; and violence including fighting and use of weapons, (2) Improving Mammography Screening in Oklahoma, (3) the treatment of incontinence in women using interferential therapy, (4) The doctor-patient relationship and its role in adherence and other positive patient outcomes, and (5) Domestic violence/ partner abuse - impact on pregnancy outcomes and barriers to screening in primary care.
|
John D. Ash, Ph.D.
E-Mail Dr. Ash
|
OUHSC: Cell Biology,
Neuroscience,
Ophthalmology
|
Cytokine regulation of neuronal differentiation in the retina, Stress-activated cytokine regulation of normal and pathological vascular development within the eye.
|
Top of the Page
|
B (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Doris M. Benbrook, Ph.D.
E-Mail Dr. Benbrook
|
OUHSC: Obstetrics & Gynecology,
Biochemistry & Molecular Biology
|
Cancer prevention, tumorigenesis, transcriptional regulation, nuclear receptors, apoptosis, differentiation, retinoids, radiosensitization, and drug development.
|
Denise G. Bender, J.D., P.T.
E-Mail Prof. Bender
|
OUHSC: Rehabilitation Science,
Geriatric Medicine
|
Legal issues affecting community dwelling older adults; end-of-life education.
|
Ari Berkowitz, Ph.D.
E-Mail Dr. Berkowitz
|
Norman: Zoology;
OUHSC: Neuroscience
|
Neural basis of behavioral choice, motor pattern selection, sensorimotor integration, broad tuning/ population coding, generation of rhythmic motor patterns, and spinal cord neurophysiology/ neuroanatomy.
|
Sanjay I. Bidichandani,
M.B.B.S., Ph.D.
E-Mail Dr. Bidichandani
|
OUHSC: Biochemistry & Molecular Biology
|
Friedreich ataxia and characterizing the genetic properties of the GAA triplet-repeat expansion and understanding the function of frataxin.
|
Ira Blader, Ph.D.
E-Mail Dr. Blader
|
OUHSC: Microbiology & Immunology,
Member of Genomics & Bioinformatics Program,
Neuroscience
|
Cell Biology and Immunology of the Host Pathogen Interaction. We use microarrays, siRNA screens, cell biology, and immunology to identify molecular mechanisms underlying how Toxoplasma gondii causes disease in humans.
|
Barbara L. Bonner, Ph.D.
E-Mail Dr. Bonner
|
OUHSC: Pediatrics
|
Child abuse related fatalities; treatment outcome in children's mental health; program evaluation; and health services outcome research.
|
Sylvia S. Bottomley, M.D.
E-Mail Dr. Bottomley
|
OUHSC: Medicine
|
Pathophysiologic mechanisms in the sideroblastic anemias including (1) proteomics of erythroid ALA synthase mutants, (2) regulation of erythroid heme biosynthesis, and (3) cause of the associated erythropoietic hemochromatosis.
|
David W.A. Bourne, B.Pharm., M.S., Ph.D.
E-Mail Dr. Bourne
|
OUHSC: Pharmacy;
OSU: Oklahoma State University Center for Veterinary Health Sciences
|
Pharmacokinetics, Drug Analysis (HPLC), some Dosage Form Development and Testing, Computer applications to teaching and research.
|
Robert H. Broyles, Ph.D.
E-Mail Dr. Broyles
|
OUHSC: Biochemistry & Molecular Biology;
OMRF: Free Radical Biology & Aging
|
(1) Gene regulation/repression of the human beta-globin gene as a treatment for sickle cell disease and (2) Cancer/long-term liver organ cultures for investigating hepatocarcinogenesis.
|
Top of the Page
|
C (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Michelle C. Callegan, Ph.D.
E-Mail Dr. Callegan
|
OUHSC: Ophthalmology,
Microbiology & Immunology,
Neuroscience
|
Host/pathogen interactions in ocular infectious diseases, bacterial toxin effects on retinal cell physiology, multi-antibiotic resistance in ocular infectious disease.
|
Wei Cao, M.D., Ph.D.
E-Mail Dr. Cao
|
OUHSC: Ophthalmology
|
Seek to understand the mechanisms of photoreceptor cell death and survival in mammalian retina and to elucidate the role of other types of cell such as, Müller cells or RPE, on photoreceptor survival. Particularly interested in the survival factors/small molecules that are involved in neuroprotection or rescue. Also interested in understanding how these signaling regulate neuronal survival and inhibit apoptosis.
|
J. Donald Capra, M.D.(President, OMRF)
E-Mail Dr. Capra
|
OMRF (President):Molecular Immunogenetics;
OUHSC: Microbiology & Immunology
|
B cell development, V(D)J recombination, mucosal immunity, and immunotherapeutics.
|
Bruce A. Carnes, Ph.D.
E-Mail Dr. Carnes
|
OUHSC: Geriatric Medicine
|
Biodemography of aging with a specific focus on the interspecies comparison and prediction of age-related patterns of mortality.
|
Daniel J. J. Carr, Ph.D.
E-Mail Dr. Carr
|
OUHSC: Neuroscience,
Ophthalmology
|
Cellular immunology, neuroimmunology, viral immunology, ocular inflammation, anti-viral compounds, and DNA vaccines.
|
Michael Centola, Ph.D.
E-Mail Dr. Centola
|
OMRF: Arthritis & Immunology
|
Molecular, cellular, and genomics studies of human autoinflammatory disease. We perform gene expression profiling using microarrays to define new effector and regulatory genes, physiologic systems of dysfunction, as well as novel molecular-based classification schemes of human autoimmune and autoinflammatory disease.
|
Brian P. Ceresa, Ph.D.
E-Mail Dr. Ceresa
|
OUHSC: Cell Biology,
Cancer Institute
|
Signal transduction, membrane trafficking, epidermal growth factor receptor (EGFR), small molecular weight G-proteins, and endocytosis.
|
Mark J. Chaffin, Ph.D.
E-Mail Dr. Chaffin
|
OUHSC: Pediatrics,
Psychiatry & Behavioral Sciences
|
Child maltreatment, service delivery systems, effectiveness outcome research.
|
James Chodosh, M.D.
E-Mail Dr. Chodosh
|
OUHSC: Ophthalmology,
Cell Biology,
Microbiology & Immunology
|
Virology and mucosal immunology of the external eye, corneal cell biology and immunology.
|
Margaret Clarke, Ph.D.
E-Mail Dr. Clarke
|
OMRF: Molecular, Cell, and Developmental Biology;
OUHSC: Cell Biology
|
Motility of cells and intracellular organelles.
|
K. Mark Coggeshall, Ph.D.
E-Mail Dr. Coggeshall
|
OMRF: Immunobiology & Cancer;
OUHSC: Cell Biology,
Microbiology & Immunology
|
The nature and identity of negative signaling enzymes, their mechanisms of activation, and their influences on the biology of hematopoietic cells.
|
Kenneth Copeland, M.D.
E-Mail Dr. Copeland
|
OUHSC: Pediatrics
|
Most research within the section of Diabetes/ Endocrinology pertains to disorders of growth and diabetes, particularly those involving Native American children and adolescents. Formal partnerships between the OU Children’s Diabetes Center and several Native American tribes have been established for research and clinical services, with care provided onsite at tribal health centers across Oklahoma.
|
James R. Couch, M.D.
E-Mail Dr. Couch
|
OUHSC: Neurology (Chair)
|
Research interests are in headache and stroke. Actively involved in clinical drug trials in both of these areas.
|
Dan F. Criswell, M.D.
E-Mail Dr. Criswell
|
OUHSC: Family and Community Medicine
|
Handheld/desktop computer applications in family practice, primary care practice-based research.
|
Daniel J. Culkin, M.D.
E-Mail Dr. Culkin
|
OUHSC: Urology (Chair)
|
Interstitial cystitis, urologic cancers, prostate problems.
|
Richard D. Cummings, Ph.D.
E-Mail Dr. Cummings
|
OUHSC: Biochemistry & Molecular Biology,
Cancer Institute,
Oklahoma Center for Medical Glycobiology
|
Receptors, signaling, cell adhesion, inflammatory diseases, carbohydrate-binding proteins, and glycoconjugates.
|
Madeleine W. Cunningham, Ph.D.
E-Mail Dr. Cunningham
|
OUHSC: Microbiology & Immunology
|
Molecular mimicry, autoimmunity, and infection and study of the molecular and immunological basis for mimicry between cardiac myosin and infectious agents causing anitimmune sequelae as well as to understand how cardiac myosin functions as an autoantigen in the heart.
|
Top of the Page
|
D (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Paul L. DeAngelis, Ph.D.
E-Mail Dr. DeAngelis
|
OUHSC: Biochemistry and Molecular Biology
|
Glycobiology, polysaccharides, hyaluronan, heparin, chondroitin, synthases, enzymology, biomaterials and biotechnology, bacterial capsules, and virulence.
|
Lawrence E. DeBault, Ph.D.
E-Mail Dr. DeBault
|
OUHSC: Pathology
|
My current research interests related to the injury and repair, and the de-differentiation and differentiation of reactive cells of the microvasculature and of weight bearing cartilage.
|
William C. Dooley, M.D., F.A.C.S.
E-Mail Dr. Dooley
|
OUHSC: Surgery
|
Aneuploidy generation and perpetuation in carcinogenesis, image cytometry, immunohistochemical prognostic markers for breast cancer, ductal lavage and the intra-ductal approach to chemoprevention and therapy of breast cancer, hyperthermia including phased array microwave as adjuvant to chemotherapy and/or radiation therapy.
|
Kenneth J. Dormer, M.S., Ph.D.
E-Mail Dr. Dormer
|
OUHSC: Physiology
|
Integrative biology, implantable medical devices, biomaterials, auditory biomechanics, cellular adhesion proteins, epithelial adhesion, bio-nanotechnology, and targeted drug delivery using nanoparticles.
|
Michael E. Dresser, M.D., Ph.D.
E-Mail Dr. Dresser
|
OMRF: Molecular, Cell, and Developmental Biology;
OUHSC: Cell Biology
|
Chromosome structure/function, chromosome segregation, image and motion analysis, telomere, meiosis, DNA repair, and recombination.
|
Douglas A. Drevets, M.D., D.T.M.& H.
E-Mail Dr. Drevets
|
OUHSC: Medicine,
Microbiology & Immunology
|
Listeria monocytogenes pathogenesis, meningitis, mouse monocyte/macrophage function.
|
David W. Dyer, Ph.D.
E-Mail Dr. Dyer
|
OUHSC: Microbiology & Immunology
|
Microbial pathogenesis, bacterial iron transport, genome sequencing, sequence analysis/annotation, microarray fabrication and analysis, proteomics, microbial responses to host factors, and microbial ecology.
|
Top of the Page
Top of the Page
|
F (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Jay P. Farber, Ph.D.
E-Mail Dr. Farber
|
OUHSC: Physiology
|
Respiratory Neurobiology: spinal cord integration of respiratory and non-respiratory inputs by respiration-related interneurons and respiratory motor outflows; development of respiratory control.
|
A. Darise Farris, Ph.D.
E-Mail Dr. Farris
|
OMRF: Arthritis & Immunology;
OUHSC: Microbiology & Immunology,
Pathology
|
Normal mechanisms of immune tolerance to nuclear autoantigens, particularly T helper cell tolerance; etiology and pathogenesis of systemic autoimmune diseases, especially lupus and Sjogren's syndrome; mouse models of tolerance and autoimmunity; microarray analysis of tolerant lymphocytes.
|
Joseph Ferretti, Ph.D. (Senior Vice President and Provost, OUHSC)
E-Mail Dr. Ferretti
|
OUHSC: Microbiology & Immunology
|
Streptococcal infection, infectious disease, and genomics.
|
Robert A. Floyd, Ph.D.
E-Mail Dr. Floyd
|
OMRF: Free Radical Biology & Aging;
OUHSC Biochemistry & Molecular Biology, Neuroscience
|
Role of oxygen-free radicals in brain aging and pathological mechanisms of neurodegenerative diseases and dementia associated with advanced stages of AIDS infection; signal transduction processes in diseases of aging, the involvement of reactive oxygen species in these events and the action of MAP kinases ad phosphatases in these events; the involvement of mitochondrial changes in choline deficiency-induced liver tumor and development in model systems; the mechanistic basis of the neuroprotective action of a-phenyl-tert-butylnitrone (PBN) in model systems of brain aging and the disease of aging, and; the biological consequences of oxidative damage to DNA, both nuclear and mitochondrial.
|
Robert D. Foreman, Ph.D.
E-Mail Dr. Foreman
|
OUHSC: Physiology (Chair),
Neuroscience,
Anesthesiology
|
Neuro-Humoral Mechanisms of Visceral Dysfunction: neural hierarchy and cardiac and respiratory control; visceral pain, angina pectoris, myocardial ischemia, sudden cardiac death, cardiac inflammation, heart failure; stress and diseases of visceral organs--ischemic heart disease, irritable bowel syndrome; cross-sensitization between visceral organs; and mechanisms of pain relief using treatments such as spinal cord stimulation. Many of these projects are conducted with the International Working Group on Neurocardiology.
|
Mark D. Fox, M.D., Ph.D.
E-Mail Dr. Fox
|
OUHSC: Medicine,
Pediatrics;
OU-Tulsa: Oklahoma Bioethics Center
|
Ethics, health policy, organ transplantation policy (organ donation and allocation).
|
Bart Frank, Ph.D.
E-Mail Dr. Frank
|
OMRF: Arthritis & Immunology;
OUHSC: Microbiology & Immunology
|
Gene expression profiles in rheumatic and autoimmune diseases; microarrays.
|
Bryan P. Fuller, Ph.D.
E-Mail Dr. Fuller
|
OUHSC: Biochemistry & Molecular Biology
|
Regulation of gene expression by hormones, hormonal regulation of human pigmentation genes, regulation of inflammatory responses in skin by UV, and development of topical formulations for dermatology applications.
|
Beverly W. Funderburk, Ph.D.
E-Mail Dr. Funderburk
|
OUHSC: Pediatrics
|
Parent-Child Interaction Therapy, specifically applications for children at high risk for abuse and therapist training issues.
|
Top of the Page
|
G (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Doug Gaffin, Ph.D.
E-Mail Dr. Gaffin
|
Norman: Zoology;
OUHSC: Neuroscience
|
Sensory biology of scorpions; Electrophysiological examination of synaptic
integration in mid-ventral chemosensory organs (pectines); Behavioral
analysis of chemo-, mechano-, and visual cues used in orientation to mates,
food sources, and home burrows.
|
Randle Gallucci, Ph.D.
E-Mail Dr. Gallucci
|
OUHSC: Pharmacology & Toxicology,
Pharmaceutical Sciences
|
Molecular immunopharmacology and toxicology and the roles of cytokines in healing and damage processes.
|
David Garrison, Ph.D.
E-Mail Dr. Garrison
|
OUHSC: Rehabilitation Science
|
Neuromodulation of pain mechanisms and cognitive imagery training in rehabilitation.
|
Larry P. Gonzalez, Ph.D.
E-Mail Dr. Gonzalez
|
OUHSC: Psychiatry & Behavioral Sciences,
Neuroscience
|
Neuropsychopharmacology, behavioral and electrophysiological correlates of CNS drug action, in vivo and in vitro electrophysiology, cDNA arrays and gene expression, alcohol, drugs of abuse, chronic drug exposure, withdrawals, and seizures.
|
Gary J. Gorbsky, Ph.D.
E-Mail Dr. Gorbsky
|
OMRF: Molecular, Cell, and Developmental Biology;
OUHSC: Cell Biology
|
Cell cycle checkpoints, mitosis, meiosis, anti-cancer drug development, topoisomerase II, microtubule dynamics, chromosome movement, genetic instability in birth defects and cancer, mitotic and meiotic chromosome assembly and function, and signal transduction.
|
Beverley Greenwood-Van Meerveld, Ph.D., F.A.C.G.
E-Mail Dr. Greenwood-Van Meerveld
|
OUHSC: Neuroscience (Director),
Physiology,
Psychiatry & Behavioral Sciences,
Pharmacology & Toxicology;
VA: Digestive Disease Physiology
|
Brain-gastrointestinal axis and the pharmacological emphasis from the molecular level to the whole animal.
|
Mary Kay Gumerlock, M.D.
E-Mail Dr. Gumerlock
|
OUHSC: Neurosurgery
|
Brain Tumors, Blood-Brain Barrier, Cerebrovascular Disease, Hydrocephalus.
|
Qing Guo, M.D., Ph.D.
E-Mail Dr. Guo
|
OUHSC: Physiology
|
Cytogenetic mechanisms of neurodegenerative disorders (Alzheimer’s disease, Amyotrophic lateral sclerosis), gene targeting, gene transfer and protein expression, proteomics, generation and characterization of transgenic animals, molecular and cellular analysis of neuronal apoptotic pathways.
|
Top of the Page
|
H (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Toby Ballou Hamilton, Ph.D., OTR/L
E-Mail Dr. Hamilton
|
OUHSC: Rehabilitation Science
|
The role of personal narratives in promoting naturally occurring Occupational Adaptation during life transitions; The process of adaptation related to performance of everyday activities; Study of personal narratives of life, health, illness, and effects on performance of everyday activities; Application of qualitative methodology to the study of adaptation and narrative.
|
Robert M. Hamm, Ph.D.
E-Mail Dr. Hamm
|
OUHSC: Family & Preventive Medicine,
Epidemiology & Biostatistics
|
(1) How medical decisions ought to be made (decision analysis, cost effectiveness analysis), and (2) how medical decisions actually are made (the psychology of decision making on the part of both doctors and patients). Decision analysis of screening and treatment for prostate cancer and for cervical cancer. How patients evaluate outcomes in the near versus far future. How physicians understand the statistics included in journal papers.
|
Jay Hanas, Ph.D.
E-Mail Dr. Hanas
|
OUHSC: Biochemistry & Molecular Biology
|
Analysis of protein-DNA and protein-protein interactions in eukaryotic gene transcription; elucidating mechanistic effects of toxic substances on animal gene expression; tumor progression systems, and; the evolution of eukaryotic gene regulatory proteins as a model for network synergy.
|
Marie H. Hanigan, Ph.D.
E-Mail Dr. Hanigan
|
OUHSC: Cell Biology,
Cancer Institute,
Obstetrics and Gynecology
|
Cancer chemotherapy, ovarian cancer, drug resistance, drug metabolism, cisplatin, nephrotoxicity, antioxidants, glutathione metabolism, gamma-glutamyl transpeptidase, carcinogenesis, initiation and promotion of tumors, and tumor progression.
|
John B. Harley, M.D., Ph.D.
E-Mail Dr. Harley
|
OMRF: Arthritis & Immunology;
OUHSC: Medicine,
Microbiology & Immunology,
Neuroscience,
Pathology
|
Systematic lupus erythematosus and the Epstein Barr virus.
|
Randall S. Hewes, Ph.D.
E-Mail Dr. Hewes
|
Norman: Zoology;
OUHSC: Cell Biology,
Neuroscience
|
Long-term regulation of neuropeptide levels in Drosophila and mice;
Regulation of peptidergic cell development and function by basic
helix-loop-helix proteins; Genetic models of neuroendocrine disease, and;
Genome scale mutagenesis.
|
William H. Hildebrand, Ph.D.
E-Mail Dr. Hildebrand
|
OUHSC: Microbiology & Immunology
|
Determination of how the human immune response targets virus infected and tumor cells, characterizing differences in human leukocyte antigens (HLA) from person to person, and how HLA differences impact bone marrow and solid organ (heart, kidney, etc.) transplantation.
|
Ute Hochgeschwender, M.D.
E-Mail Dr. Hochgeschwender
|
OMRF: Molecular, Cell, and Developmental Biology;
OUHSC: Cell Biology,
Neuroscience
|
Research on the POMC-deficient mouse model to gain new insights into obesity, diabetes, pituitary tumors, adrenal development, and endocrine regulation.
|
Frank A. Holloway, Ph.D.
E-Mail Dr. Holloway
|
OUHSC: Psychiatry & Behavioral Sciences,
Neuroscience
|
Behavioral pharmacology of abused drugs and behavioral neurosciences.
|
Eric W. Howard, Ph.D.
E-Mail Dr. Howard
|
OUHSC: Cell Biology,
Neuroscience
|
The molecular basis for matrix metalloproteinase-mediated cell migration and invasion; the regulation of angiogenesis; the development of potent toxins targeted against invading tumor cells and angiogenic endothelial cells; wound healing; post-transcriptional regulation of gene expression.
|
Robert E. Hurst, Ph.D.
E-Mail Dr. Hurst
|
OUHSC: Urology,
Biochemistry & Molecular Biology,
Physiology
|
Cancer invasion and metastasis, carcinogenesis, mechanisms of suppression of the malignant phenotype, retinoids and other drugs that suppress the emergent cancer phenotype, cancer biomarkers, organization and differentiation of bladder epithelium, and systems biology with proteomics and transcriptomics. Lab/Urology Research.
|
Top of the Page
I (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
John J. Iandolo, Ph.D.
E-Mail Dr. Iandolo
|
OUHSC: Microbiology & Immunology (Chair)
|
Staphyloccus aureus genomics and gene expression, staphylococcal bacteriophage genetics, bacteriocin antibiotic gene expression, regulation and mode of action. Biology of Bdellovibrio bacteriovoris.
|
Michael A. Ihnat, Ph.D., R.Ph.
E-Mail Dr. Ihnat
|
OUHSC: Cell Biology
|
Angiogenesis, or blood vessel formation from pre-formed vessels, in the context of cancer; developing drugs that interfere with angiogenesis; ways to mimic tumor angiogenesis in vitro, or on the benchtop, and mechanistically how thalidomide, a known anti-angiogenic drug, exerts its action.
|
Top of the Page
J (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Judith James, M.D., Ph.D.
E-Mail Dr. James
|
OMRF: Arthritis & Immunology;
OUHSC: Medicine,
Pathology
|
Development of autoantibodies and their role in the autoimmune diseases; Pathogenic mechanisms of systemic lupus erythematosus, scleroderma, Wegener's granulomatosis, and rheumatoid arthritis.
|
Jim Jarvis, M.D.
E-Mail Dr. Jarvis
|
OUHSC: Pediatrics,
Microbiology and Immunology
|
(1) Application of genomic technologies to complex human illnesses; (2) Immunology and genetics of rheumatic disease in Native Americans.
|
David L. Johnson, Ph.D., P.E., D.E.E., C.I.H.
E-Mail Dr. Johnson
|
OUHSC: Occupational & Environmental Health (Chair)
|
Occupational and environmental exposure assessment, aerosol science, indoor air quality, and inhalation toxicology.
|
Gary A. Johnson, M.D.
E-Mail Dr. Johnson
|
OUHSC: Obstetrics & Gynecology-Oncology
|
Reproductive cancers and palliative care.
|
Top of the Page
|
K (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Kenneth Kaufman, Ph.D.
E-Mail Dr. Kaufmank
|
OMRF:
Arthritis & Immunology Research Program;
OUHSC Medicine,
VA Medical Center
|
Identification of genetic mutations leading to susceptibility to Systemic lupus erythematosus and molecular mechanism involved in the pathogenesis of autoimmune disease.
|
David C. Kem, M.D.
E-Mail Dr. Kem
|
OUHSC: Endocrinology,
Medicine
|
G-protein receptor signal transduction, especially oriented to cardiovascular tissues. Tow applications include the effect of diabetes (hyperglycemia) on the interaction of the G-protein and tyrosine kinase systems; and the impact of ischemia on cardiac function and electrophysiology. Clinical research is oriented to diagnostic and therapeutic issues in endocrine hypertension.
|
Paul W. Kincade, Ph.D.
E-Mail Dr. Kincade
|
OMRF: Immunobiology and Cancer;
OUHSC: Microbiology & Immunology
|
Immune system development, molecular control of blood cell formation, hematopoietic stem cells and progenitors, sex steroids, and cell-cell recognition.
|
Rosemary Knapp, Ph.D.
E-Mail Dr. Knapp
|
Norman: Zoology
|
Neuroendocrine mediation of reproductive and aggressive behavior, with a focus on interactions between androgens and glucocorticoids.
|
Hlapang A Kolobe, Ph.D., P.T.
E-Mail Dr. Kolobe
|
OUHSC: Rehabilitation Science
|
Early identification of children at risk for developmental disabilities; cross-cultural validation of childrearing measures; interaction between biological and environmental influences on outcome of infants and toddlers with disabilities.
|
Yashige Kotake, Ph.D.
E-Mail Dr. Kotake
|
OMRF: Free Radical Biology & Aging;
OUHSC: Pharmaceutical Sciences
|
Research interest is focused on the mechanism by which natural and synthetic antioxidants protect our body from free radical damage.
|
Bradley P. Kropp, M.D., F.A.C.S., F.A.A.P.
E-Mail Dr. Kropp
|
OUHSC: Urology
|
Tissue Engineering for Urologic organs and bladder smooth muscle physiology.
|
Shinichiro Kurosawa, M.D., Ph.D.
E-Mail Dr. Kurosawa
|
OMRF: Free Radical Biology & Aging;
OUHSC: Pathology
|
Regulation of inflammatory reactions by protein C pathway, A novel marker of hypercoagulable state, Pathogenesis of Wegener's Granulomatosis.
|
Top of the Page
|
L (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Vicki T. Lampley, M.D., M.P.H.
E-Mail Dr. Lampley
|
OUHSC: Geriatric Medicine
|
Ethnicity and dementia and their caregivers (disparities in the health care of demented minorities, caregiver stress in minority caregivers, early diagnosis, bias in testing) and barriers to recruiting African Americans and Native Americans for research studies.
|
Marc E. P. Lenaerts, M.D.
E-Mail Dr. Lenaerts
|
OUHSC: Neurology
|
Clinical research in the field of headache: therapeutic trials (triptans, magnesium, vitamin B2); effect of vagus nerve and occipital nerve stimulation in headaches; genetics of migraine; comorbidity in migraine.
|
Guangpu Li, Ph.D.
E-Mail Dr. Li
|
OUHSC: Biochemistry & Molecular Biology
|
GTPase-mediated intracellular trafficking, signal transduction pathways, and regulation of Sindbis virus replication.
|
Jialing Lin, Ph.D.
E-Mail Dr. Lin@ouhsc.edu
|
OUHSC: Biochemistry & Molecular Biology
|
Apoptosis and determine the functional native Bcl-2 structure in organelle membranes and the intracellular proteins that interact with Bcl-2.
|
Yuechueng Liu, Ph.D.
E-Mail Dr. Liu
|
OUHSC: Pathology,
Neuroscience
|
Neuronal signal transduction, axonal growth and regeneration, neurotransmitter release, synaptogenesis, and neural degenerative diseases.
|
Thomas Lock, M.D.
E-Mail Dr. Lock
|
OUHSC: Pediatrics
|
Attention-Deficit/Hyperacitvity disorder; Development of Functional Independence in children; Developmental disabilities.
|
William R. Lovallo, Ph.D.
E-Mail Dr. Lovallo
|
OUHSC: Psychiatry & Behavioral Sciences,
Neuroscience
|
Central nervous system processes relating behavioral stress, emotions, cognitive responses to patterns of endocrine and autonomic outflow; understand the role of emotions in health and disease.
|
Top of the Page
|
M (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Rex E. Martin, Ph.D.
E-Mail Dr. Martin
|
OUHSC: Cell Biology,
Neuroscience,
Ophthalmology
|
How do dietary essential fatty acids potentiate development of brain and retina? How can they be neuroprotective yet cast off when cells are stressed? Cell fractionation, tissue culture, TLC, HPLC, and GC correlate disease and damage with lipid metabolism in subcellular compartments and lipid microdomains of brain and retina.
|
Hiroyuki Matsumoto, Ph.D.
E-Mail Dr. Matsumoto
|
OUHSC: Biochemistry & Molecular Biology,
Neuroscience
|
Protein phosphorylation cascades in the compounds eyes of Drosophila; regulation of InaD protein, a member of PDZ family, by multiple phosphorylation; protein phosphorylation cascades in vertebrate photoreceptors; catalog of vertebrate retinal proteins, and; development of microscale biochemical analysis by mass spectrometry.
|
Laine H. McCarthy, M.L.I.S.
E-Mail Laine McCarthy
|
OUHSC: Family Medicine
|
Primary care health policy research. Currently studying Medicaid reform issues in Oklahoma.
|
Rodger P. McEver, M.D.(Co-Director, M.D./ Ph.D. Program)
E-Mail Dr. McEver
|
OMRF: Cardiovascular Biology;
OUHSC: Biochemistry & Molecular Biology
|
Cell adhesion, protein-carbohydrate interactions, selectins, vascular biology, inflammation, hemostasis, immunology, leukocytes, platelets, and endothelial cells.
|
Irene McEwen, Ph.D., P.T.
E-Mail Dr. McEwen
|
OUHSC: Rehabilitation Science
|
Measurement of outcomes of intervention for children with disabilities; effects of assistive technology on the development of children with disabilities.
|
James F. McGinnis, Ph.D.
E-Mail Dr. McGinnis
|
OUHSC: Ophthalmology,
Cell Biology,
Neuroscience
|
Signal transduction pathways involved in apoptosis and rescue of photoreceptor cells; molecular mechanisms of antibody mediated death of retinal neurons; identification of transcription factors, response elements, and analysis of gene promoters, and; molecular basis of light-dependent subcellular movement of retinal proteins in photoreceptor cells.
|
Patrick A. McKee, M.D.
E-Mail Dr. McKee
|
OUHSC: Medicine
|
Thrombolysis; fibrinolysis; biochemistry of fibrin formation and removal; protease inhibitors; atherogenesis.
|
W. Michael McShan, Ph.D.
E-Mail Dr. McShan
|
OUHSC: Pharmaceutical Sciences
|
The genetics of Streptococcus pyogenes, mismatch repair and evolution, the regulation of extracellular toxins, genomics.
|
William H. Meyer, M.D.
E-Mail Dr. Meyer
|
OUHSC: Pediatrics
|
Clinical therapeutic trials in rhabdomyosarcoma and soft tissue sarcomas; therapeutic trials in pediatric solid tumors.
|
James W. Mold, M.D., M.P.H.
E-Mail Dr. Mold
|
OUHSC: Family & Preventive Medicine
|
Research Interests (general): primary care practice-based research, geriatrics, prevention. Specific Projects: night sweats, peripheral neuropathy, delivery of preventive services, health risk appraisal, non-adherence to practice guidelines, continuity of care.
|
Kevin L. Moore, M.D.
E-Mail Dr. Moore
|
OMRF: Cardiovascular Biology;
OUHSC: Cell Biology,
Medicine
|
Enzymology and biology of post-translational tyrosine sulfation.
|
John J. Mulvihill, M.D.
E-Mail Dr. Mulvihill
|
OUHSC: Pediatrics,
Human Genetics
|
Interdisciplinary clinical research on human/medical genetics: e.g., gene mapping by family studies; ecogenetic origins of pancreatic cancer; cytogenetics and molecular genetics of congenital heart disease and cancer; human germ cell mutagenesis.
|
Dean Myers, Ph.D.
E-Mail Dr. Myers
|
OUHSC: Physiology,
Neuroscience,
Obstetrics & Gynecology
|
Regulation of proopiomelanocortin (POMC) processing by prohormone convertases; role of ACTH and other POMC-derived peptides in regulating adrenal cortex development; regulation of glucocorticoid receptor expression, and; neurobiology of stress and stress-related behaviors.
|
Top of the Page
N (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Muna Naash, Ph.D.
E-Mail Dr. Naash
|
OUHSC: Cell Biology,
Neuroscience
|
Our research is clinically oriented and divided into three parts: (1) Application of gene therapy using either viral vectors or non viral DNA-compacted nanoparticles to combat cancers and ocular diseases. (2) Studying the pathogenic defects associated with disease-causing-mutations in photoreceptor genes using transgenic mouse technology. (3) Studying the structural and functional role of peripherin/rds in building the rim region of the photoreceptor outer segments of rods and cones. These studies involve biochemical, molecular biology, genetic manipulations and gene therapy approaches.
|
Zsolt Nagykaldi, Ph.D.
E-Mail Dr. Nagykaldi
|
OUHSC: Family & Preventive Medicine
|
Primary care practice enhancement and clinical research focused on preventative medicine and chronic care.
|
Top of the Page
Top of the Page
|
P (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
J. Thomas Pento, Ph.D.
E-Mail Dr. Pento
|
OUHSC: Pharmaceutical Sciences,
Pharmacology and Toxicology
|
The development of chemopreventive strategies designed to control or prevent the metastatic process in breast cancer.
|
H. Anne Pereira, Ph.D.
E-Mail Dr. Pereira
|
OUHSC: Pathology,
Cell Biology,
Neuroscience,
Surgery
|
Inflammation, leukocyte biology, leukocyte emigration, leukocyte-endothelial interactions, antimicrobial peptides, sepsis, atherosclerosis, Alzheimer's disease, and neuroinflammation.
|
Betty Pfefferbaum, M.D., J.D.
E-Mail Dr. Pfefferbaum
|
OUHSC: Psychiatry & Behavioral Sciences (Chair)
|
Child and adolescent psychiatry; trauma and disasters.
|
Margaret L. Phillips, Ph.D.
E-Mail Dr. Phillips
|
OUHSC: Occupational and Environmental Health
|
Assessment of exposure to occupational and environmental health hazards.
|
Su An Arnn Phipps, R.N., Ph.D.
E-Mail Dr. Phipps
|
OUHSC: Nursing
|
Health Care Dispairities, Family Resiliency, Diabetes during Pregnancy.
|
Scott M. Plafker, Ph.D.
E-Mail Dr. Plafker
|
OUHSC: Cell Biology,
Cancer Institute
|
Our laboratory studies the role of the ubiquitin proteolytic system in cell division, development, and bacterial pathogenesis. We use interdisciplinary approaches and experimental systems in our studies including live-cell microscopy, recombinant protein assays, and most recently, the zebrafish vertebrate model system.
|
Top of the Page
Q (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Lurdes Queimado, M.D., Ph.D.
E-Mail Dr. Queimado
|
OUHSC: Otorhinolaryngology
|
Cancer research, DNA repair, transcription regulation and salivary gland tumors. Currently we focus our work on two projects: (1) DNA repair deficiencies are causally associated with cancer. In contrast, an increase in DNA repair capacity in some cancer cells has been associated with higher resistance to chemo and radiotherapy. We have identified a novel gene, MMS19, which regulates DNA repair and transcription. We are studying MMS19 function and its possible role in human cancer. (2) Molecular characterization of salivary gland tumors.
|
Top of the Page
|
R (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Raju V.S. Rajala, Ph.D.
E-Mail Dr. Rajala
|
OUHSC: Ophthalmology,
Cell Biology
|
Role of light and insulin receptor in the activation of phosphoinositide 3-kinase in the retina. N-myristoylation of unique retinal proteins. Protein-protein interactions.
|
James B. Rand, Ph.D.
E-Mail Dr. Rand
|
OMRF: Molecular, Cell, and Developmental Biology;
OUHSC: Cell Biology,
Neuroscience
|
Neurotransmitter synthesis and transport into synaptic vesicles; mechanisms and regulation of neurotransmitter release in C. elegans.
|
James L. Regens, Ph.D.
E-Mail Dr. Regens
|
OUHSC: Occupational & Environmental Health
|
Risk assessment, modeling/simulation, and decision analysis of chemical/biological/ radiological/nuclear terrorism countermeasures, infectious disease transmission dynamics, environmental health.
|
William G. Reiner, M.D.
E-Mail Dr. Reiner
|
OUHSC: Urology,
Psychiatry & Behavioral Sciences
|
Psychosocial and psychosexual development in children with major genitourinary birth defects.
|
Antonio M. C. Reis, M.D.
E-Mail Dr. Reis
|
OUHSC: Dermatology
|
DNA damage, DNA repair, mutagenesis, basic cancer research, molecular studies in mice and humans; developed a new assay to detect DNA damage at the single nucleotide/strand/allele/cell level (main focus of my current work); preliminary results based on use of skin DNA from Xpc mutant mice are promising; because little is known about DNA damage and because many common human diseases, including cancers, may arise from unrepaired DNA damage,
this new assay may provide new information about the repair capacity and levels of DNA damage in some individuals, thus providing a possible link between individual levels of DNA damage and some human conditions.
|
Malcolm Robinson, M.D., F.A.C.P., F.A.C.G.
E-Mail Dr. Robinson
|
OUHSC: Medicine
|
Clinical investigation in gastroesophageal reflux disease, functional bowel disorders, inflammatory bowel disease, gastrointestinal physiology and clinical pharmacology.
|
Karla Rodgers, Ph.D.
E-Mail Dr. Rodgers
|
OUHSC: Biochemistry & Molecular Biology
|
V(D)J recombination, structure and function of the recombination-activatingproteins RAG1 and RAG2, protein-DNA interactions, zinc-binding proteins.
|
Elliott D. Ross, M.D.
E-Mail Dr. Ross
|
OUHSC: Neurology,
Communication Sciences,
Geriatrics,
Neuroscience,
Psychiatry & Behavioral Sciences;
VA: Center for Alzheimer’s & Neurodegenerative Disorders
|
Neurological basis of language, prosody, emotions, affect and memory; cognitive changes associated with aging and dementia; acoustical analysis of speech in various clinical populations.
|
Top of the Page
|
S (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Ricardo Saban, D.V.M., Ph.D.
E-Mail Dr. Saban
|
OUHSC: Physiology,
Neuroscience
|
Our primary research focus is to determine tissue-specific genes and promoters involved in lymphoangiogenesis. For this purpose, we are using four transgenic mouse models (Blood 2004, 104: 3228-3230) to define the urinary bladder transcriptome during cancer development and in response to BCG therapy.
|
Michael Sakalian, Ph.D.
E-Mail Dr. Sakalian
|
OUHSC: Microbiology & Immunology
|
Virus molecular biology, virus replication, virus-cell interactions, retrovirus assembly, and antiviral agents.
|
Jorge F. Saucedo, M.D., M.B.A.
E-Mail Dr. Saucedo
|
OUHSC: Medicine
|
Improving cardiovascular outcomes in the adult population by utilizing new therapies, techniques, or devices in association with acute and chronic coronary artery disease; Angiogenesis and its application in critical leg ischemia and chronic coronary artery disease; Platelets function and participation in acute coronary syndromes and ischemic events following percutaneous coronary interventions.
|
Eliot Schechter, M.D.
E-Mail Dr. Schechter
|
OUHSC:Medicine
|
Invasive and Interventional Cardiology; Coronary disease; Valvular Disease.
|
Dewey Scheid, M.D., M.P.H.
E-Mail Dr. Scheid
|
OUHSC: Family & Preventive Medicine
|
Medical decision making, computerized decision support, quality improvement
|
R. Hal Scofield, M.D.
E-Mail Dr. Scofield
|
OMRF: Arthritis and Immunology;
OUHSC: Medicine,
William K. Warren Medical Research Institute
|
The immunology and genetics of systemic autoimmune diseases including (1) spondyloarthropathies such as ankylosing spondylitis, which are strongly associated with HLA-B27 and (2) systemic lupus erythematosus and Sjorgen's syndrome.
|
Jim Scott, Ph.D.
E-Mail Dr. Scott
|
OUHSC: Psychiatry & Behavioral Science
|
Relationship of neurologic disease to changes in cognition and behavior. Effect of Neurosurgery on cognitive functioning. Evaluation of cognitive deficits in Neurodegenerative disorders.
|
Thomas W. Seale, Ph.D.
E-Mail Dr. Seale
|
OUHSC: Pediatrics
|
Genetics and molecular biology of Haemophilus influenzae; iron acquisition by bacterial pathogens; animal models of disease.
|
Kris Sekar, M.D.
E-Mail Dr. Sekar
|
OUHSC: Pediatrics
|
Inhaled nitric oxide in neonates for the prevention of chronic lung disease.
|
Nathan Shankar, Ph.D.
E-Mail Dr. Shankar
|
OUHSC: Pharmaceutical Sciences,
Pharmacology & Toxicology
|
Enterococcus faecalis, virulence factors of Gram positive bacteria, pathogenicity islands, bacterial surface proteins and toxins, drug design using genomic approaches, and antibiotic resistance.
|
Fátima de N. Abrantes Pais Shelton, M.D.
E-Mail Dr. Shelton
|
OUHSC: Neurology;
VA: Rehabilitation Research & Development
|
Cognitive aspects of disability and recovery after CNS insults; Motor recovery after neurological injuries; Stroke-rehabilitation outcomes.
|
Jane F. Silovsky, Ph.D.
E-Mail Dr. Silovsky
|
OUHSC: Pediatrics
|
Treatment outcome research and program evaluations of services for children affected by child maltreatment and other traumatic events.
|
Puneet Sindhwani, M.D.
E-Mail Dr. Sindhwani
|
OUHSC: Urology
|
Nutrition and cancer, novel intravesical agents for bladder cancer, male infertility and renal transplantation.
|
Garth L. Splinter, M.D., M.B.A.
E-Mail Dr. Splinter
|
OUHSC: Family Medicine
|
Primary care health policy research. Currently studying Medicaid reform issues in Oklahoma.
|
Regina M. Sullivan, Ph.D.
E-Mail Dr. Sullivan
|
Norman: Zoology;
OUHSC: Neuroscience
|
Neurobehavioral development, mother-infant interactions, learning, attachment, olfactory development, somatosensory development, amygdala, locus coeruleus, and norepinephrine.
|
Xiao-Hong Sun, Ph.D.
E-Mail Dr. Sun
|
OMRF: Immunobiology & Cancer;
OUHSC: Cell Biology,
Microbiology & Immunology
|
Transcription factors, lymphocyte development, leukemia, cytokine-regulated gene expression, and signal transduction.
|
Lisa M. Swisher, Ph.D.
E-Mail Dr. Swisher
|
OUHSC: Pediatrics
|
Youth with inappropriate or illegal sexual behavior, juvenile delinquency, and maltreated children.
|
Top of the Page
|
T (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Jordan Tang, Ph.D.
E-Mail Dr. Tang
|
OMRF: Protein Studies;
OUHSC: Biochemistry & Molecular Biology
|
Aspartic proteases, Alzheimer's disease, protease in the pathogenesis of Alzheimer's disease, physiological function of new human aspartic proteases, HIV protease, inhibitor design, molecular basis of HIV drug resistance, and structure and function relationships of proteins.
|
Ann M. Thompson, Ph.D.
E-Mail Dr. Thompson
|
OUHSC: Otorhinolaryngology,
Cell Biology
|
Studying the neural circuits and neurotransmitters of the adult and developing mammalian central auditory system. The current focus is on the role of serotonin as a trophic factor in the development of auditory brainstem nuclei and function.
|
Linda F. Thompson, Ph.D.
E-Mail Dr. Thompson
|
OMRF: Immunobiology & Cancer;
OUHSC: Microbiology & Immunology
|
Lymphocyte development, murine models of immunodeficiency diseases (especially adenosine deaminase deficiency), adenosine receptors, purine metabolism (normal and inborn errors), function of CD73 (ecto-5'-nucleotidase), glycosyl phosphatidylinositol membrane anchors, and human thymocyte development.
|
James J. Tomasek, Ph.D.
E-Mail Dr. Tomasek
|
OUHSC: Cell Biology
|
Our laboratory studies the molecular mechanisms regulating the interplay of mechanical stress and actin dynamics regulating gene expression important in wound healing and tissue repair. We also are performing structure-function studies on the actin isoforms. We use both whole animal (transgenic and knockout mouse models) and single cell experimental models applying molecular and cell biology techniques.
|
Leo Tsiokas, Ph.D.
E-Mail Dr. Tsiokas
|
OUHSC: Cell Biology,
William K. Warren Medical Research Institute
|
Molecular and cellular biology of autosomal dominant polycystic kidney disease.
|
Martin A. Turman, M.D., Ph.D.
E-Mail Dr. Turman
|
OUHSC: Pediatrics, Cell Biology
|
Discovered that renal cells produce the peptide hormone somatostatin and the lab is now studying the ability of somatostatin to alter cyst formation in polycystic kidney disease. Also examining the cell signaling pathways involved in regulation of alpha smooth muscle actin as normal kidney tubular epithelial cells transition to become myofibroblasts during renal fibrosis, a common endpoint for many forms or kidney disease, such as diabetic nephropathy and polycystic kidney disease. These studies utilize primary cultures of human kidney tubular and cystic epithelial cells isolated from patients.
|
Rodney K. Tweten, Ph.D.
E-Mail Dr. Tweten
|
OUHSC: Microbiology & Immunology
|
Structural biology of bacterial toxins, identification of toxin receptors, the mechanism of membrane insertion of bacterial pore-forming toxins, and the molecular engineering of bacterial toxins for specific uses.
|
Top of the Page
Top of the Page
Top of the Page
|
W (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Joan L. Walker, M.D.
E-Mail Dr. Walker
|
OUHSC: Obstetrics & Gynecology
|
Gynecologic cancer prevention, screening, diagnosis and treatment. (1) Cervix cancer prevention has been my primary focus, with HPV testing and triage on the ASCUS/LSIL Triage Study. We are now under contract with NCI to develop a tissue bank for micro-array. (2) Evaluation of symptoms and the timely diagnosis of ovarian cancer is a grant we have with the Center for Disease Control. (3) We have clinical trials for the treatment of cervix cancer, endometrial cancer, uterine sarcoma, vulvar cancer, and gestational trophoblastic disease. We participate on the NCI funded Gynecologic Oncology Group(GOG) trials.
|
Joseph L. Waner, Ph.D.
E-Mail Dr. Waner
|
OUHSC: Pediatrics
|
Clinical virology; molecular detection of viruses; respiratory viruses.
|
Han Wang, Ph.D.
E-Mail Dr. Wang
|
Norman: Zoology
|
Zebrafish (Danio rerio) development genetics and genomics, circadian rhythmicity and blood development.
|
Julia 'Jill' K. Warnock, M.D., Ph.D.
E-Mail Dr. Warnock
|
Tulsa: Psychiatry
|
Mood Disorders; Psychopharmacology; Sexual Disorders in Women; Reproductive Endocrinology-specifically the impact of the sex steroids in women with depression and with sexual dysfunction.
|
Carol F. Webb, Ph.D.
E-Mail Dr. Webb
|
OMRF: Immunobiology & Cancer;
OUHSC: Cell Biology,
Microbiology & Immunology
|
Immunodeficiency disease, B lymphocyte differentiation, immunoglobulin gene regulation, transcription factors, chromatin structure, nuclear matrix, matrix association regions, intracellular signaling events, the transcription factor Bright.
|
Paul Weigel, Ph.D.
E-Mail Dr. Weigel
|
OUHSC: Biochemistry & Molecular Biology (Chair)
|
Receptor mediated endocytosis and receptor recycling, hyaluronic acid (HA) synthesis and turnover, structure and functions of HA synthases and the HA Receptor for Endocytosis, and asialoglycoprotein receptor.
|
Allan F. Wiechmann, Ph.D.
E-Mail Dr. Wiechmann
|
OUHSC: Cell Biology,
Ophthalmology
|
Molecular mechanisms of circadian signaling in the retina, identification and regulation of melatonin receptors in the retina, mechanism of function of the circadian signaling molecule, melatonin, on photoreceptor function in health and disease.
|
Paul W. Whitby, Ph.D.
E-Mail Dr. Whitby
|
OUHSC: Pediatrics
|
Iron/heme acquisitions of the human pathogen Haemophilus Influenzae and virulence factors/gene regulation of Burkholderia cepacia, a pathogen of patients with cystic fibrosis.
|
Robert A. Wild, M.D., Ph.D., M.P.H.
E-Mail Dr. Wild
|
OUHSC: Obstetrics & Gynecology,
Biostatistics & Epidemiology,
Medicine
|
Women's Health, Reproductive Endocrinology (Polycytic Ovary Syndrome, Menopausal Health, SERMS), and Proeventive Cardiology.
|
Donald A. Wilson, Ph.D.
E-Mail Dr. Wilson
|
Norman: Zoology;
OUHSC: Neuroscience,
Psychiatry & Behavioral Sciences
|
Neurobiology of memory, perceptual learning, sensory coding in the olfactory system, ontogeny of memory, the role of experience in sensory system ontogeny.
|
Celeste R. Wirsig-Wiechmann, Ph.D.
E-Mail Dr. Wirsig
|
OUHSC: Cell Biology,
Neuroscience
|
Hormones on sensory systems; role of the sex hormone, gonadotropin-releasing hormone (GnRH), in the modulation of olfaction; evolution of pheromones, and; influence of melatonin in retinal physiology and brain functioning.
|
Mark L. Wolraich, M.D.
E-Mail Dr. Wolraich
|
OUHSC: Pediatrics
|
The diagnosis and treatment of children with Attention Deficit Hyperactivity Disorder.
|
Top of the Page
Top of the Page
Y (Researchers - Alphabetical)
Top of the Page
|
|---|
| Faculty Researcher | Department/Appointment | Research Interest |
|---|
Xiao He Yang, M.D., Ph.D.
E-Mail Dr. Yang
|
OUHSC: Pathology
|
Functional dissection of the apoptotic cascade in breast cancer. Receptor interactions amongst epithelial growth factor receptor (EGFR) family members and their role in the novel therapeutics targeting EGFR and erbB-2.
|
Top of the Page
Top of the Page
Anesthesiology
Top of the Page
|
|---|
| Faculty Researcher | Research Interest |
|---|
Robert D. Foreman, Ph.D.
E-Mail Dr. Foreman
|
Neuro-Humoral Mechanisms of Visceral Dysfunction: neural hierarchy and cardiac and respiratory control; visceral pain, angina pectoris, myocardial ischemia, sudden cardiac death, cardiac inflammation, heart failure; stress and diseases of visceral organs--ischemic heart disease, irritable bowel syndrome; cross-sensitization between visceral organs; and mechanisms of pain relief using treatments such as spinal cord stimulation. Many of these projects are conducted with the International Working Group on Neurocardiology.
|
Top of the Page
|
Biochemistry & Molecular Biology
Top of the Page
|
|---|
| Faculty Researcher | Research Interest |
|---|
Gillian Air, Ph.D.
E-Mail Dr. Air
|
Molecular approaches to control of influenza.
|
Doris M. Benbrook, Ph.D.
E-Mail Dr. Benbrook
|
Cancer prevention, tumorigenesis, transcriptional regulation, nuclear receptors, apoptosis, differentiation, retinoids, radiosensitization, and drug development.
|
Sanjay I. Bidichandani,
M.B.B.S., Ph.D.
E-Mail Dr. Bidichandani
|
Friedreich ataxia and characterizing the genetic properties of the GAA triplet-repeat expansion and understanding the function of frataxin.
|
Robert H. Broyles, Ph.D.
E-Mail Dr. Broyles
|
(1) Gene regulation/repression of the human beta-globin gene as a treatment for sickle cell disease and (2) Cancer/long-term liver organ cultures for investigating hepatocarcinogenesis.
|
Richard D. Cummings, Ph.D.
E-Mail Dr. Cummings
|
Receptors, signaling, cell adhesion, inflammatory diseases, carbohydrate-binding proteins, and glycoconjugates.
|
Paul L. DeAngelis, Ph.D.
E-Mail Dr. DeAngelis
|
Glycobiology, polysaccharides, hyaluronan, heparin, chondroitin, synthases, enzymology, biomaterials and biotechnology, bacterial capsules, and virulence.
|
Charles T. Esmon, Ph.D.
E-Mail Dr. Esmon
|
Current research focuses on the regulation of blood coagulation by the protein C anticoagulant pathway and the cross-talk between this pathway and acute inflammatory responses.
|
Robert A. Floyd, Ph.D.
E-Mail Dr. Floyd
|
Role of oxygen-free radicals in brain aging and pathological mechanisms of neurodegenerative diseases and dementia associated with advanced stages of AIDS infection; signal transduction processes in diseases of aging, the involvement of reactive oxygen species in these events and the action of MAP kinases ad phosphatases in these events; the involvement of mitochondrial changes in choline deficiency-induced liver tumor and development in model systems; the mechanistic basis of the neuroprotective action of a-phenyl-tert-butylnitrone (PBN) in model systems of brain aging and the disease of aging, and; the biological consequences of oxidative damage to DNA, both nuclear and mitochondrial.
|
Bryan P. Fuller, Ph.D.
E-Mail Dr. Fuller
|
Regulation of gene expression by hormones, hormonal regulation of human pigmentation genes, regulation of inflammatory responses in skin by UV, and development of topical formulations for dermatology applications.
|
Jay Hanas, Ph.D.
E-Mail Dr. Hanas
|
Analysis of protein-DNA and protein-protein interactions in eukaryotic gene transcription; elucidating mechanistic effects of toxic substances on animal gene expression; tumor progression systems, and; the evolution of eukaryotic gene regulatory proteins as a model for network synergy.
|
Robert E. Hurst, Ph.D.
E-Mail Dr. Hurst
|
Cancer invasion and metastasis, carcinogenesis, mechanisms of suppression of the malignant phenotype, retinoids and other drugs that suppress the emergent cancer phenotype, cancer biomarkers, organization and differentiation of bladder epithelium, and systems biology with proteomics and transcriptomics. Lab/Urology Research.
|
Guangpu Li, Ph.D.
Guangpu-Li@ouhsc.edu
|
GTPase-mediated intracellular trafficking, signal transduction pathways, and regulation of Sindbis virus replication.
|
Jialing Lin, Ph.D.
E-Mail Dr. Lin
|
Apoptosis and determine the functional native Bcl-2 structure in organelle membranes and the intracellular proteins that interact with Bcl-2.
|
Hiroyuki Matsumoto, Ph.D.
E-Mail Dr. Matsumoto
|
Protein phosphorylation cascades in the compounds eyes of Drosophila; regulation of InaD protein, a member of PDZ family, by multiple phosphorylation; protein phosphorylation cascades in vertebrate photoreceptors; catalog of vertebrate retinal proteins, and; development of microscale biochemical analysis by mass spectrometry.
|
Rodger P. McEver, M.D. (Co-Director, M.D./ Ph.D. Program)
E-Mail Dr. McEver
|
Cell adhesion, protein-carbohydrate interactions, selectins, vascular biology, inflammation, hemostasis, immunology, leukocytes, platelets, and endothelial cells.
|
Ann Louise Olson, Ph.D.
E-Mail Dr. Olson
|
Insulin receptor signaling, gene regulation, and molecular biology of glucose transporter regulation.
|
Karla Rodgers, Ph.D.
E-Mail Dr. Rodgers
|
V(D)J recombination, structure and function of the recombination-activatingproteins RAG1 and RAG2, protein-DNA interactions, zinc-binding proteins.
|
Jordan Tang, Ph.D.
E-Mail Dr. Tang
|
Aspartic proteases, Alzheimer's disease, protease in the pathogenesis of Alzheimer's disease, physiological function of new human aspartic proteases, HIV protease, inhibitor design, molecular basis of HIV drug resistance, and structure and function relationships of proteins.
|
Paul Weigel, Ph.D. (Chair)
E-Mail Dr. Weigel
|
Receptor mediated endocytosis and receptor recycling, hyaluronic acid (HA) synthesis and turnover, structure and functions of HA synthases and the HA Receptor for Endocytosis, and asialoglycoprotein receptor.
|
Adam Zlotnick, Ph.D.
E-Mail Dr. Zlotnick
|
Physical and structural basis of virus capsid assembly and protein-protein interaction.
|
Top of the Page
Biostatistics & Epidemiology
Top of the Page
|
|---|
| Faculty Researcher | Research Interest |
|---|
June E. Eichner, Ph.D.
E-Mail Dr. Eichner
|
Cardiovascular disease, chronic disease, prevention research, human genetics.
|
Robert M. Hamm, Ph.D.
E-Mail Dr. Hamm
|
(1) How medical decisions ought to be made (decision analysis, cost effectiveness analysis), and (2) how medical decisions actually are made (the psychology of decision making on the part of both doctors and patients). Decision analysis of screening and treatment for prostate cancer and for cervical cancer. How patients evaluate outcomes in the near versus far future. How physicians understand the statistics included in journal papers.
|
Robert A. Wild, M.D., Ph.D., M.P.H.
E-Mail Dr. Wild
|
Women's Health, Reproductive Endocrinology (Polycytic Ovary Syndrome, Menopausal Health, SERMS), and Proeventive Cardiology.
|
Top of the Page
|
Cancer Institute
Top of the Page
|
|---|
| Faculty Researcher | Research Interest |
|---|
Brian P. Ceresa, Ph.D.
E-Mail Dr. Ceresa
|
Signal transduction, membrane trafficking, epidermal growth factor receptor (EGFR), small molecular weight G-proteins, and endocytosis.
|
Richard D. Cummings, Ph.D.
E-Mail Dr. Cummings
|
Receptors, signaling, cell adhesion, inflammatory diseases, carbohydrate-binding proteins, and glycoconjugates.
|
Marie H. Hanigan, Ph.D.
E-Mail Dr. Hanigan
|
Cancer chemotherapy, ovarian cancer, drug resistance, drug metabolism, cisplatin, nephrotoxicity, antioxidants, glutathione metabolism, gamma-glutamyl transpeptidase, carcinogenesis, initiation and promotion of tumors, and tumor progression.
|
Scott M. Plafker, Ph.D.
E-Mail Dr. Plafker
|
Our laboratory studies the role of the ubiquitin proteolytic system in cell division, development, and bacterial pathogenesis. We use interdisciplinary approaches and experimental systems in our studies including live-cell microscopy, recombinant protein assays, and most recently, the zebrafish vertebrate model system.
|
Top of the Page
| |
|
