The OUHSC Blood and Bone Marrow Transplant Program performs transplants at 3 Oklahoma Health Science Center Hospitals which are all adjacent buildings within two square blocks. Each unit has its own separate nursing, pharmacy, and hospital staff.

• University Hospital (UH)
  Located on the 10th floor Everett Tower, the UH BMT Unit officially opened in 1986. It has 4 laminar airflow rooms designed for patients undergoing allogeneic transplants and 4 other regular hospital rooms adequate for autologous transplants. The unit and its nursing staff are intensive-care-capable with a nurse-to-patient ratio of 1:1 or 1:2 most of the time. Telemetry monitors are also available when needed. There is an adjacent bone marrow processing laboratory equipped to freeze and thaw grafts at appropriate times. A conference room is also available for chart rounds of the staff. Two family waiting rooms include a smaller private one and a larger informal one with television.

• Children's Hospital of Oklahoma (CHO)
  Located as part of the Pediatric Intensive Care Unit on the 6th floor of Garrison Tower, the pediatric unit has two HEPA-filtered ICU-type rooms. Pediatric autologous and allogeneic transplants are done in these rooms with support from the Pediatric Hematology/Oncology team and the CHO paramedical support team (including child psychologists, play therapists, social workers and child life personnel). Pediatric critical care physicians are also called into the team approach of services for transplant patients requiring intensive care.

• Presbyterian Hospital (PH)
  The PH BMT Unit is housed in the 7th floor West wing of the hospital and has 6 HEPA-filtered beds two of which are intensive-care ready. Two additional rooms designed for outpatient examination or day-treatment are built next to the unit across a multi-purpose conference room. Autologous hematopoietic transplants are primarily performed in this unit.

• Oklahoma Blood Institute (OBI)
  Blood and blood component therapy support is provided mainly by the Oklahoma Blood Institute, a non-profit organization with a large network of blood product collection and distribution centers serving most of the state of Oklahoma. The OBI performs the collection of peripheral blood stem cells by leukapheresis for the OUHSC BMT program. The OBI, a National Marrow Donor Program donor marrow collection center utilizes the staff of the OUHSC BMT program for harvesting of donor bone marrow for the unrelated donor registry.